Mukul Midha

Research Scientist

Dr. Midha’s research is focused onto understanding the early events which activate the development of metabolic disorders using different quantitative proteomics strategies, in particular with high resolution mass spectrometry.  Dr. Midha studied the molecular mechanism associated with obesity and diabetes signaling pathways in mouse models and received his PhD from Immunology department, International Centre for Genetic Engineering and Biotechnology, India in 2013.  Post PhD, he joined as a Research Associate at THSTI, India and worked on SWATH-MS for absolute quantification of mycobacterial proteins during human macrophage infection.  He joined ISB in 2016 as a Post-Doctoral fellow.  His current interests are standardizing and implementing different chromatography and MS setups in the field of label free quantitative proteomics.

  • Proteomics
  • Mass Spectrometry


Shweta Duggal, Noor Jailkhania, Mukul Kumar Midha, Kanury V.S. Rao, Ajay Kumar. 2017. Defining the Akt1 interactome data and delineating alterations in its composition as a function of cell cycle progression. Data in Brief.


Ajay Kumar, Shilpa Jamwal, Mukul Kumar Midha, Baseerat Hamza, Suruchi Aggarwal, Amit Kumar Yadav, Kanury VS Rao. 2016. Dataset generated using hyperplexing and click chemistry to monitor temporal dynamics of newly synthesized macrophage secretome post infection by mycobacterial strains. Data in Brief.


Ajit G. Chande, Zaved Siddiqui, Mukul Kumar Midha, Varsha Sirhoi, Srikanth Ravichandran and Kanury V. S. Rao. 2015. Selective enrichment of mycobacterial proteins from infected host macrophages through genetic incorporation of azidonorleucine. Scientific Reports 5, DOI: 10.1038/srep13430.

NM Saquib, Shilpa Jamwal, Mukul Kumar Midha, Hridaya narayan Verma  and Venkatasamy Manivel *.2015. Quantitative Proteomics and Lipidomics Analysis of Endoplasmic Reticulum of Macrophage Infected with Mycobacterium tuberculosis. International journal of proteomics,


Shilpa Jamwal , Mukul Kumar Midha , Hridaya narayan Verma , Atanu Basu , Kanury V. S Rao and  Venkatasamy Manivel*. 2013. Characterizing virulence-specific perturbations in the mitochondrial function of macrophages infected with Mycobacterium tuberculosis. Scientific Reports, DOI: 10.1038/srep01328.


Mukul Kumar Midha, Kamiya Tikoo, Neeraj Sinha, Simarjeet Kaur, Hirdya Narain Verma, Kanury V.S. Rao, Samrat Chatterjee* and Venkatasamy Manivel*. 2012.  Extracting Time-Dependent Obese-diabetic Specific Networks in Hepatic Proteome Analysis. Journal of Proteome Research. DOI: 10.1021/pr300711a